Tocris/SU 5402/3300/1/1毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/SU 5402/3300/1/1毫克

Tocris/SU 5402/3300/1/1毫克

商品编号： 3300/1

品牌： Tocris Bioscience

市场价： ¥4500.00

美元价： 2700.00

产地：美国(厂家直采)

公司：

产品分类：激酶

公司分类： kinase

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentFGFRandVEGFRinhibitor

ChemicalName:2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoicacid

Purity:≥95%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivevascularendothelialgrowthfactorreceptor(VEGFR)andfibroblastgrowthfactorreceptor(FGFR)inhibitor(IC₅₀valuesare0.02,0.03,0.51and>100μMatVEGFR2,FGFR1,PDGFRβandEGFRrespectively).Inhibitsembryonicleft-rightdeterminationandexhibitspotentanticanceractivityinvitroandinvivo.Alsoattenuatesintegrinβ4-induceddifferentiationofneuralstemcells.

TechnicalData

M.Wt	296.32
Formula	C₁₇H₁₆N₂O₃
Storage	Storeat-20°C
Purity	≥95%(HPLC)
CASNumber	215543-92-3
PubChemID	5289418
InChIKey	JNDVEAXZWJIOKB-JYRVWZFOSA-N
Smiles	CC1=CNC(C=C(C2=CC=CC=C2N3)/C3=O)=C1CCC(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	29.63	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight296.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.37mL	16.87mL	33.75mL
5mM	0.67mL	3.37mL	6.75mL
10mM	0.34mL	1.69mL	3.37mL
50mM	0.07mL	0.34mL	0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets