Biological Activity
Selective antagonist at GABAB receptors.
Technical Data
| M. Wt | 249.72 |
| Formula | C9H12ClNO3S |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 125464-42-8 |
| PubChem ID | 122150 |
| InChI Key | JYLNVJYYQQXNEK-UHFFFAOYSA-N |
| Smiles | NCC(CS(O)(=O)=O)C1=CC=C(Cl)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 6.24 | 25 | |
| water | 2.5 | 10 |
Preparing Stock Solutions
The following data is based on the product molecular weight 249.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4 mL | 20.02 mL | 40.04 mL |
| 5 mM | 0.8 mL | 4 mL | 8.01 mL |
| 10 mM | 0.4 mL | 2 mL | 4 mL |
| 50 mM | 0.08 mL | 0.4 mL | 0.8 mL |
Molarity Calculator
Reconstitution Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Bowery (1989) GABAB receptors and their significance in mammalian pharmacology. TiPS 10 401 PMID: 2559518
Jane et al (1990) Use of the neonatal rat spinal cord in studies of the GABAB receptor. GABAB receptors in Mammalian Function. 42b PMID:
Keywords: Saclofen, supplier, Selective, GABAB, antagonists, Receptors, GABAB, Receptors, GABAB, Receptors, Tocris Bioscience
