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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/Sazetidine A dihydrochloride/2736/10/10 mg
商品详细Tocris/Sazetidine A dihydrochloride/2736/10/10 mg
Tocris/Sazetidine A dihydrochloride/2736/10/10 mg
Tocris/Sazetidine A dihydrochloride/2736/10/10 mg
商品编号: 2736/10
品牌: Tocris Bioscience
市场价: ¥3780.00
美元价: 2268.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:α4β2receptorligand;mayactasanagoNISToradesensitizer
ChemicalName:6-[5-[(2S)-2-Azetidinylmethoxy]-3-pyridinyl]-5-hexyn-1-oldihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Subtype-selectiveα4β2nicotinicacetylcholinereceptorligand(Kivaluesare0.26and54nMatα4β2andα3β4receptorsrespectively).Mayactasasilentdesensitizerorasanagonist,dependingonsubunitstoichiometry(EC50=1.1nMfornAChR-stimulateddopaminerelease).Exhibitsanalgesicactivityinvivoandsignificantlyreducesnicotineself-administrationinanexperimentalratmodel.

TechnicalData

M.Wt333.25
FormulaC15H20N2O2.2HCl
StorageDesiccateat+4°C
Purity≥98%(HPLC)
CASNumber1197329-42-2
PubChemID56972183
InChIKeyWRSKKJWUXISFFU-UTLKBRERSA-N
SmilesOCCCCC#CC1=CN=CC(OC[C@H]2NCC2)=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water16.6650

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight333.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3mL15mL30.01mL
5mM0.6mL3mL6mL
10mM0.3mL1.5mL3mL
50mM0.06mL0.3mL0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet