Biological Activity
Glycine agonist at the NMDA receptor. L-Serine (Cat. No. 0227) also available.
Technical Data
| M. Wt | 105.09 |
| Formula | C3H7NO3 |
| Storage | Store at RT |
| CAS Number | 312-84-5 |
| PubChem ID | 71077 |
| InChI Key | MTCFGRXMJLQNBG-UWTATZPHSA-N |
| Smiles | N[C@@]([H])([C@](O)=O)CO |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 105.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 9.52 mL | 47.58 mL | 95.16 mL |
| 5 mM | 1.9 mL | 9.52 mL | 19.03 mL |
| 10 mM | 0.95 mL | 4.76 mL | 9.52 mL |
| 50 mM | 0.19 mL | 0.95 mL | 1.9 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Schell et al (1997) D-Serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors. J. Neurosci. 17 1604 PMID: 9030620
Lodge (1989) Non-competitive NMDA antagonists. The NMDA Receptor (2nd edition). Eds. G.L.Collingr 37 PMID:
Mothet et al (2000) D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc.Natl.Acad.Sci.USA 97 4926 PMID: 10781100
Keywords: D-Serine, supplier, Potentiator, glycine, site, Glutamate, NMDA, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, NMDA, Receptors, NMDA, Receptors, Tocris Bioscience
