Tocris/ShK-Dap22/3220/100U/100 ug-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/ShK-Dap22/3220/100U/100 ug

Tocris/ShK-Dap22/3220/100U/100 ug

商品编号： 3220/100U

品牌： Tocris Bioscience

市场价： ¥5100.00

美元价： 3060.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:ExtremelypotentandselectiveK_V1.3blocker;suppressesTcellactivationinvitro

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ExtremelypotentK_V1.3channelblocker(K_d=23pMformK_V1.3currents).SelectiveforK_V1.3overothermammalianpotassiumchannels(IC₅₀valuesare23,1800,10500,37000and39000pMformK_V1.3,mK_V1.1,hK_V1.6,mK_V1.4andrK_V1.2respectively,and>100000pMforhK_V1.5,mK_V1.7,hK_V3.1,rK_V3.4andhK_Ca4).SuppressesTcellactivationinvitro(IC₅₀<500pM).

TechnicalData

M.Wt	4012.7
Formula	C₁₆₆H₂₆₈N₅₄O₄₈S₇
Sequence	RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC (Modifications:Disulfidebridges:3-35,12-28,17-32),X=Dap)
Storage	Storeat-20°C
CASNumber	220384-25-8
PubChemID	122187345
InChIKey	PFWOJTLVNOZSGQ-RIMJLNMDSA-N
Smiles	[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@H](CN)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)[C@H](CC4=CNC=N4)NC(=O)[C@H](CCCCN)NC3=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC1=O)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)O)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto1mg/mlinwater

Solubility

Solubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight4012.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.25mL	1.25mL	2.49mL
5mM	0.05mL	0.25mL	0.5mL
10mM	0.02mL	0.12mL	0.25mL
50mM	0mL	0.02mL	0.05mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets