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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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4000-520-616
当前位置: 首页 > 产品中心 > protease > Tocris/Sivelesta钠盐/3535/50/50 mg
商品详细Tocris/Sivelesta钠盐/3535/50/50 mg
Tocris/Sivelesta钠盐/3535/50/50 mg
Tocris/Sivelesta钠盐/3535/50/50 mg
商品编号: 3535/50
品牌: Tocris Bioscience
市场价: ¥9100.00
美元价: 5460.00
产地: 美国(厂家直采)
公司:
产品分类: 蛋白酶类
公司分类: protease
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Selectiveleukocyteelastaseinhibitor
AlternativeNames:ONO-5046
ChemicalName:N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycinesodiumsalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveleukocyteelastaseinhibitor(IC50=44nM)thatdisplaysnoactivityatarangeofotherproteases.InhibitsNF-κBactivationandLTB4-inducedneutrophiltransmigrationinvitro.Significantlyattenuatesischemia-inducedspinalcordinjury,decreasesserumcytokinelevelsandreducesacuteinflammatorylunginjuryinvivo.

CompoundLibraries

SivelestatsodiumsaltisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt456.44
FormulaC20H21N2NaO7S
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber150374-95-1
PubChemID23664980
InChIKeyZAIFANJZUGNYCK-UHFFFAOYSA-M
Smiles[Na+].CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC1=CC=CC=C1C(=O)NCC([O-])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.8250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight456.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.19mL10.95mL21.91mL
5mM0.44mL2.19mL4.38mL
10mM0.22mL1.1mL2.19mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet