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Tocris/Src I1/3642/50/50 mg

商品编号： 3642/50

品牌： Tocris Bioscience

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:DualsiteSrckinaseinhibitor

ChemicalName:6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,competitivedualsite(ATP-andpeptide-binding)Srckinaseinhibitor(IC₅₀valuesare44and88nMforSrcandLckrespectively).InhibitsVEGFR2andc-fmsathigherconcentrations(IC₅₀valuesare0.32and30μMrespectively).CanbeusedinparallelwithPP1(Cat.No.1397)andPP2(Cat.No.1407)toinhibitSrcfamilykinases.

CompoundLibraries

SrcI1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	373.4
Formula	C₂₂H₁₉N₃O₃
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	179248-59-0
PubChemID	1474853
InChIKey	DMWVGXGXHPOEPT-UHFFFAOYSA-N
Smiles	COC(C(OC)=C3)=CC1=C3N=CN=C1NC2=CC=C(OC4=CC=CC=C4)C=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	37.34	100
	ethanol	1.87	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight373.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.68mL	13.39mL	26.78mL
5mM	0.54mL	2.68mL	5.36mL
10mM	0.27mL	1.34mL	2.68mL
50mM	0.05mL	0.27mL	0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets