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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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4000-520-616
当前位置: 首页 > 产品中心 > Receptors > Tocris/Stressin I/1608/500U/500微克
商品详细Tocris/Stressin I/1608/500U/500微克
Tocris/Stressin I/1608/500U/500微克
Tocris/Stressin I/1608/500U/500微克
商品编号: 1608/500U
品牌: Tocris Bioscience
市场价: ¥7380.00
美元价: 4428.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:CRF1agoNIST
AlternativeNames:cyclo(31-34)[D-Phe12,Nle21,38,Glu31,Lys34]Ac-hCRF(4-41)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivecorticotropinreleasingfactorreceptor-1(CRF1)agonist(Kivaluesare1.5and224nMforCRF1andCRF2receptorsrespectively).IncreasesACTHlevelsandincreasesfaecalpelletoutputinvivofollowingi.p.administration.

LicensingInformation

SoldwiththepermissionoftheSALKInstitute

TechnicalData

M.Wt4472.24
FormulaC203H337N57O56
SequencePPISLDLTFHLLREVLEXARAEQLAQQEHSKRKLXEII

(Modifications:Pro-1=N-terminalAc,X=Nle,Glu-28=γ-Glu,Lys-31=ε-Lys,Cyclized=Glu-28-Lys-31,Ile-38=C-terminalamide)

StorageDesiccateat-20°C
PubChemID90479815
InChIKeyHZKFMBAUDWRPRY-WNBAZHKDSA-N
SmilesCCCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(C)=O)[C@@H](C)CC)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H]1CCC(=O)NCCCCC(NC(=O)[C@H](CO)NC(=O)[C@H](CC2=CNC=N2)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(N)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight4472.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.22mL1.12mL2.24mL
5mM0.04mL0.22mL0.45mL
10mM0.02mL0.11mL0.22mL
50mM0mL0.02mL0.04mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet