Biological Activity
Selective EP3 and EP1 receptor agonist (Ki values are 0.6 and 21 nM respectively). Synthetic PGE2 analog and allodynic agent.
Technical Data
| M. Wt | 465.56 |
| Formula | C23H31NO7S |
| Storage | Store at -20°C |
| CAS Number | 60325-46-4 |
| PubChem ID | 5312153 |
| InChI Key | UQZVCDCIMBLVNR-TWYODKAFSA-N |
| Smiles | O=C1[C@H](C/C=CCCCC(NS(=O)(C)=O)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC=C2)[C@H](O)C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble in methyl acetate (supplied pre-dissolved - 5mg/ml) |
Preparing Stock Solutions
The following data is based on the product molecular weight 465.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.15 mL | 10.74 mL | 21.48 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.3 mL |
| 10 mM | 0.21 mL | 1.07 mL | 2.15 mL |
| 50 mM | 0.04 mL | 0.21 mL | 0.43 mL |
Molarity Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Gil et al (2008) Transient allodynia pain models in mice for assessment of analgesic activity. Br.J.Pharmacol. 153 769 PMID: 17700719
Narumiya et al (1999) Prostanoid receptors: Structures, properties, and functions. Phys.Rev. 79 1193 PMID:
Keywords: Sulprostone, supplier, Sulprostone, prostaglandin, prostanoid, EP1, EP3, receptor, agonist, Prostanoid, Receptors, Prostanoid, Receptors, Tocris Bioscience
