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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/TAK 715/4254/50/50 mg
商品详细Tocris/TAK 715/4254/50/50 mg
Tocris/TAK 715/4254/50/50 mg
Tocris/TAK 715/4254/50/50 mg
商品编号: 4254/50
品牌: Tocris Bioscience
市场价: ¥16500.00
美元价: 9900.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potentp38MAPKinhibitor;anti-inflammatory
ChemicalName:N-[4-[2-Ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofp38MAPK(IC50=7.1nMforp38MAPKα).AlsoinhibitsWnt-3a-stimulatedβ-cateninsignaling.Inhibits22kinasesbymorethan80%,includingCK1δ/ε.Anti-inflammatoryandanti-rheumatoidarthritisagent.Orallybioavailable.

CompoundLibraries

TAK715isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt399.51
FormulaC24H21N3OS
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber303162-79-0
PubChemID90488922
InChIKeyBRYAJHADJWBFQY-UHFFFAOYSA-N
SmilesCCC1=NC(C3=CC(C)=CC=C3)=C(C2=C(NC(C4=CC=CC=C4)=O)N=CC=C2)S1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.95100
ethanol19.9850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight399.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.5mL12.52mL25.03mL
5mM0.5mL2.5mL5.01mL
10mM0.25mL1.25mL2.5mL
50mM0.05mL0.25mL0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet