Tocris/TC Mps1 12/4750/50/50 mg
商品编号：
4750/50
市场价：
¥16500.00
美元价：
9900.00
产品分类：
其它酶
公司分类：
Other_enzymes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:PotentandselectiveMps1kinaseinhibitor
ChemicalName:4-[[4-Amino-5-cyano-6-[(1,1-dimethylethyl)amino]-2-pyridinyl]amino]benzamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentandselectivemonopolarspindle1(Mps1)inhibitor(IC50=6.4nM).SelectiveforMps1overapanelof95kinasesincludingJNK.InhibitsA549lungcarcinomacellproliferationandattenuatesA549cellxenograftgrowthinmice.Orallyactive.
CompoundLibraries
TCMps112isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 324.38 |
| Formula | C17H20N6O |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 1206170-62-8 |
| PubChemID | 70682875 |
| InChIKey | XDEFNAWAKYQBQY-UHFFFAOYSA-N |
| Smiles | NC1=C(C#N)C(NC(C)(C)C)=NC(NC2=CC=C(C(N)=O)C=C2)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 32.44 | 100 | |
| ethanol | 6.49 | 20mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight324.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.08mL | 15.41mL | 30.83mL |
| 5mM | 0.62mL | 3.08mL | 6.17mL |
| 10mM | 0.31mL | 1.54mL | 3.08mL |
| 50mM | 0.06mL | 0.31mL | 0.62mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet