Tocris/TCS PIM-1 4a/3714/10/10 mg
商品编号：
3714/10
市场价：
¥1980.00
美元价：
1188.00
产品分类：
其它酶
公司分类：
Other_enzymes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:Selective,ATP-competitivePimkinaseinhibitor
AlternativeNames:SMI-4a
ChemicalName:(5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Selective,ATP-competitivePimkinaseinhibitor(IC50valuesare24and100nMforPim-1andPim-2respectively).Displaysselectivityoverapanelof~50otherkinasestested.ExhibitscytotoxicityinPC3prostatecarcinomacellsinvitro(IC50=17μM).
TechnicalData
| M.Wt | 273.23 |
| Formula | C11H6F3NO2S |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 438190-29-5 |
| PubChemID | 1361334 |
| InChIKey | NGJLOFCOEOHFKQ-YVMONPNESA-N |
| Smiles | O=C(/C(S2)=C/C1=CC(C(F)(F)F)=CC=C1)NC2=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.32 | 100 | |
| ethanol | 27.32 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight273.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.66mL | 18.3mL | 36.6mL |
| 5mM | 0.73mL | 3.66mL | 7.32mL |
| 10mM | 0.37mL | 1.83mL | 3.66mL |
| 50mM | 0.07mL | 0.37mL | 0.73mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet