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商品详细Tocris/TFB-TBOA/2532/1/1 mg

Tocris/TFB-TBOA/2532/1/1 mg

商品编号： 2532/1

品牌： Tocris Bioscience

市场价： ¥2580.00

美元价： 1548.00

产地：美国(厂家直采)

公司：

产品分类：转运体

公司分类： Transporters

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HighaffinityEAAT1andEAAT2blocker

ChemicalName:(3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-asparticacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveglialglutamatetransporterEAAT1andEAAT2inhibitor(IC₅₀valuesare17,22and300nMforEAAT2,EAAT1andEAAT3respectively).HasnoeffectonEAAT4andEAAT5,orawiderangeofneuronalreceptorsandtransporters.Attenuatesglutamate-stimulatedintracellularNa⁺elevationinastrocytesinvitro(IC50=43nM).Inducessevereconvulsionsinvivo.

LicensingInformation

SoldforresearchpurposesunderlicensefromSuntoryLtd.

TechnicalData

M.Wt	426.35
Formula	C₁₉H₁₇F₃N₂O₆
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	480439-73-4
PubChemID	52941382
InChIKey	LPWONNPEPDHEAI-GJZGRUSLSA-N
Smiles	OC([C@@H](N)[C@H](OCC1=CC=CC(NC(C2=CC=C(C(F)(F)F)C=C2)=O)=C1)C(O)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	42.63	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight426.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.35mL	11.73mL	23.45mL
5mM	0.47mL	2.35mL	4.69mL
10mM	0.23mL	1.17mL	2.35mL
50mM	0.05mL	0.23mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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