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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/TFC 007/5108/50/50毫克
商品详细Tocris/TFC 007/5108/50/50毫克
Tocris/TFC 007/5108/50/50毫克
Tocris/TFC 007/5108/50/50毫克
商品编号: 5108/50
品牌: Tocris Bioscience
市场价: ¥16900.00
美元价: 10140.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotenthematopoieticprostaglandinDsynthase(H-PGDS)inhibitor
ChemicalName:N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotenthematopoieticprostaglandinDsynthase(H-PGDS)inhibitor(IC50=83nM).InhibitsPGD2productionandlatephasenasalblockageinananimalmodelofallergicrhinitis.ExhibitsnegligIBLeeffectsonCOX-1,COX-2,5-LOX,LTC4synthase,TXA2synthaseandmicrosomalprostaglandinE2synthase.

CompoundLibraries

TFC007isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt487.55
FormulaC27H29N5O4
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber927878-49-7
PubChemID16040067
InChIKeyNLSSUSRERAMBTA-UHFFFAOYSA-N
SmilesO=C(C2CCN(C3=CC=C(NC(C4=CN=C(OC5=CC=CC=C5)N=C4)=O)C=C3)CC2)N1CCOCC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO48.76100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight487.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.05mL10.26mL20.51mL
5mM0.41mL2.05mL4.1mL
10mM0.21mL1.03mL2.05mL
50mM0.04mL0.21mL0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet