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商品详细Tocris/TNP/3946/10/10 mg

Tocris/TNP/3946/10/10 mg

商品编号： 3946/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitorofIP6K;alsoinhibitsIP3K

ChemicalName:N⁶-[(4-nitrophenyl)methyl]-N²-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ReversIBLeinositolhexakisphosphatekinase(IP6K)inhibitor(IC₅₀=0.47μMforinhibitionofInsP₇formation).Alsoinhibitsinositol1,4,5-trisphosphate3-kinase(IP3K)(IC₅₀=10.2μM).BindstotheATPbindingsiteofIP3K(K_i=4.3μM).

TechnicalData

M.Wt	443.38
Formula	C₂₀H₁₆F₃N₇O₂
Storage	Storeat+4°C
Purity	≥97%(HPLC)
CASNumber	519178-28-0
PubChemID	16760513
InChIKey	DDSBPUYZPWNNGH-UHFFFAOYSA-N
Smiles	O=[N+](C(C=C4)=CC=C4CNC1=C2C(NC=N2)=NC(NCC3=CC=CC(C(F)(F)F)=C3)=N1)[O-]

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	44.34	100
	ethanol	11.08	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight443.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.26mL	11.28mL	22.55mL
5mM	0.45mL	2.26mL	4.51mL
10mM	0.23mL	1.13mL	2.26mL
50mM	0.05mL	0.23mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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