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商品详细Tocris/TP 003/4414/10/10 mg

Tocris/TP 003/4414/10/10 mg

商品编号： 4414/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:FunctionallyselectiveGABA_Areceptor(α3subtype)partialagoNIST

ChemicalName:2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

FunctionallyselectiveGABA_Areceptor(α3subtype)partialagonist.ExhibitsaffinityforthebenzodiazepinebindingsiteonhumanGABA_Areceptors.PotentiatestheGABA(α3subtype)responseselectivelywithhighefficacy.Producesanxiolytic-likeeffectsinrodentbehavioralmodelsofanxiety.

CompoundLibraries

TP003isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	407.39
Formula	C₂₃H₁₆F₃N₃O
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	628690-75-5
PubChemID	10001434
InChIKey	SJMMDWXJSSJHOQ-UHFFFAOYSA-N
Smiles	FC1=C(C(C)(O)C)C=CN2C1=NC=C2C3=CC=C(F)C(C4=CC=C(F)C=C4C#N)=C3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	40.74	100
	ethanol	20.37	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight407.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.45mL	12.27mL	24.55mL
5mM	0.49mL	2.45mL	4.91mL
10mM	0.25mL	1.23mL	2.45mL
50mM	0.05mL	0.25mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets