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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/TRAM 39/4952/10/10 mg
商品详细Tocris/TRAM 39/4952/10/10 mg
Tocris/TRAM 39/4952/10/10 mg
Tocris/TRAM 39/4952/10/10 mg
商品编号: 4952/10
品牌: Tocris Bioscience
市场价: ¥3180.00
美元价: 1908.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentKCa3.1blocker
ChemicalName:2-Chloro-α,α-diphenylbenzeneacetonitrile
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentintermediateconductanceCa2+-activatedK+channel(KCa3.1)blocker(Kd=60nM).Hasnoeffectoncytochromep450activity.InhibitsI-EBIO-stimulatedincreasesinratarterymembranepotentialexvivo.AlsodiminishesLPS-inducedcryptidin(mammalianα-defensin)releasefrompanethcellsinvitro.

CompoundLibraries

TRAM39isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt303.78
FormulaC20H14ClN
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber197525-99-8
PubChemID9861261
InChIKeyJHNRTPKGSCVKKC-UHFFFAOYSA-N
SmilesClC(C=CC=C3)=C3C(C2=CC=CC=C2)(C#N)C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO15.4450
ethanol3.0910mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight303.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.29mL16.46mL32.92mL
5mM0.66mL3.29mL6.58mL
10mM0.33mL1.65mL3.29mL
50mM0.07mL0.33mL0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet