Biological Activity
One of the most abundant free amino acids in the brain. A partial agonist at the inhibitory glycine receptor.
Technical Data
| M. Wt | 125.14 |
| Formula | C2H7NO3S |
| Storage | Store at RT |
| CAS Number | 107-35-7 |
| PubChem ID | 1123 |
| InChI Key | XOAAWQZATWQOTB-UHFFFAOYSA-N |
| Smiles | NCCS(=O)(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 12.51 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 125.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 7.99 mL | 39.96 mL | 79.91 mL |
| 5 mM | 1.6 mL | 7.99 mL | 15.98 mL |
| 10 mM | 0.8 mL | 4 mL | 7.99 mL |
| 50 mM | 0.16 mL | 0.8 mL | 1.6 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Boldyrev et al (1999) Carnosine and taurine protect rat cerebellar granular cells from free radical damage. Neurosci.Lett. 263 169 PMID: 10213162
Chung et al (1996) Saturable disposition of taurine in the rat cerebrospinal fluid. J.Pharmacol.Exp.Ther. 276 676 PMID: 8632336
Palmi et al (1999) Potentiation of mitochondrial Ca2+ sequestration by taurine. Biochem.Pharmacol. 58 1123 PMID: 10484070
Schmieden and Betz (1995) Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 48 919 PMID: 7476923
Keywords: Taurine, supplier, Non-Selective, endogenous, glycine, receptor, partial, agonists, GlyR, Glycine, Receptors, inhibitory, amino, acid, Glycine, Receptors, Glycine, Receptors, Tocris Bioscience
