Biological Activity
Novel antidepressant, a selective inhibitor of MAO-A.
Compound Libraries
Tetrindole mesylate is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 390.54 |
| Formula | C20H26N2.CH3SO3H |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 170964-68-8 |
| PubChem ID | 54792409 |
| InChI Key | CWPNPYVNPOAMHY-UHFFFAOYSA-N |
| Smiles | CS(O)(=O)=O.C1CCC(CC1)C1=CC=C2N3CCNC4CCCC(=C34)C2=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 39.05 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 390.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.56 mL | 12.8 mL | 25.61 mL |
| 5 mM | 0.51 mL | 2.56 mL | 5.12 mL |
| 10 mM | 0.26 mL | 1.28 mL | 2.56 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.51 mL |
Molarity Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Bos et al (1995) Resolution, EPC-syntheses, absolute stereochemistry, and pharmacology of the (S)-(+)- and (R)-(-)-isomers of the MAO-A inhibitor tetrindole hydrochloride. Arch.Pharm. (Wenheim) 328 619 PMID: 7492268
Korshunov et al (2000) Hemodynamic effects of tetrindol in alert normotensive mice and rats after blockade of nitric oxide synthesis. Bull.Exp.Biol.Med. 130 777 PMID: 11177242
Medvedev et al (1994) Monoamine oxidase inhibition by novel antidepressant tetrindole. Biochem.Pharmacol. 47 303 PMID: 8304974
Keywords: Tetrindole mesylate, supplier, MAO-A, inhibitors, inhibits, Monoamine, Oxygenases, Oxidases, Monoamine, Oxidase, Adrenergic, Related, Compounds, Dopaminergic-Related, 5-HT-Related, 5-HT3, Receptors, Monoamine, Oxidase, Tocris Bioscience
