Tocris/Tolcapone/5864/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Tolcapone/5864/50/50毫克

Tocris/Tolcapone/5864/50/50毫克

商品编号： 5864/50

品牌： Tocris Bioscience

市场价： ¥6300.00

美元价： 3780.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:COMTinhibitor;alsoinhibitstransthyretinaggregation

AlternativeNames:Tasmar,Ro40-7592

ChemicalName:(3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

COMTinhibitor.InhibitsbothbrainandperipheralCOMT.Alsobindstransthyretin(TTR)withhighaffinity(K_d1andK_d2valuesare21and58nM,respectively).InhibitsTTRaggregationinhumanplasmaandpreventsTTR-inducedcytotoxicityinvitro.StABIlizesTTRinmiceandhumansinvivo.Orallybioavailable.

TechnicalData

M.Wt	273.24
Formula	C₁₄H₁₁NO₅
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	134308-13-7
PubChemID	4659569
InChIKey	MIQPIUSUKVNLNT-UHFFFAOYSA-N
Smiles	OC1=C(O)C([N+]([O-])=O)=CC(C(C2=CC=C(C)C=C2)=O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	27.32	100
	ethanol	27.32	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight273.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.66mL	18.3mL	36.6mL
5mM	0.73mL	3.66mL	7.32mL
10mM	0.37mL	1.83mL	3.66mL
50mM	0.07mL	0.37mL	0.73mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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