Tocris/Torin 1/4247/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Torin 1/4247/10/10 mg

Tocris/Torin 1/4247/10/10 mg

商品编号： 4247/10

品牌： Tocris Bioscience

市场价： ¥4980.00

美元价： 2988.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectivemTORinhibitor

ChemicalName:1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivemTORinhibitor(IC₅₀=2-10nMformTORC1andmTORC2).Displays200-foldselectivityformTORoverDNA-PK,ATMandhVps34.InducesautophagyinHeLacells.

LicensingInformation

SoldunderlicensefromWhiteheadInstituteforBiomedicalResearch.

TechnicalData

M.Wt	607.62
Formula	C₃₅H₂₈F₃N₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1222998-36-8
PubChemID	49836027
InChIKey	AKCRNFFTGXBONI-UHFFFAOYSA-N
Smiles	O=C(N5C6=CC(C(F)(F)F)=C(N7CCN(C(CC)=O)CC7)C=C6)C=CC2=C5C1=CC(C3=CN=C(C=CC=C4)C4=C3)=CC=C1N=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	0.61	1mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight607.62.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.65mL	8.23mL	16.46mL
5mM	0.33mL	1.65mL	3.29mL
10mM	0.16mL	0.82mL	1.65mL
50mM	0.03mL	0.16mL	0.33mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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