Tocris/Torin 1/4247/50/50 mg
商品编号：
4247/50
市场价：
¥20500.00
美元价：
12300.00
产品分类：
其它酶
公司分类：
Other_enzymes
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:PotentandselectivemTORinhibitor
ChemicalName:1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentandselectivemTORinhibitor(IC50=2-10nMformTORC1andmTORC2).Displays200-foldselectivityformTORoverDNA-PK,ATMandhVps34.InducesautophagyinHeLacells.
LicensingInformation
SoldunderlicensefromWhiteheadInstituteforBiomedicalResearch.
TechnicalData
| M.Wt | 607.62 |
| Formula | C35H28F3N5O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1222998-36-8 |
| PubChemID | 49836027 |
| InChIKey | AKCRNFFTGXBONI-UHFFFAOYSA-N |
| Smiles | O=C(N5C6=CC(C(F)(F)F)=C(N7CCN(C(CC)=O)CC7)C=C6)C=CC2=C5C1=CC(C3=CN=C(C=CC=C4)C4=C3)=CC=C1N=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 0.61 | 1mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight607.62.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.65mL | 8.23mL | 16.46mL |
| 5mM | 0.33mL | 1.65mL | 3.29mL |
| 10mM | 0.16mL | 0.82mL | 1.65mL |
| 50mM | 0.03mL | 0.16mL | 0.33mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet