Biological Activity
M4 selective muscarinic receptor antagonist.
Compound Libraries
Tropicamide is also offered as part of the Tocriscreen Plus and Tocriscreen Library of FDA-Approved Compounds. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 284.36 |
| Formula | C17H20N2O2 |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 1508-75-4 |
| PubChem ID | 5593 |
| InChI Key | BGDKAVGWHJFAGW-UHFFFAOYSA-N |
| Smiles | CCN(CC1=CC=NC=C1)C(=O)C(CO)C1=CC=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in DMSO |
Preparing Stock Solutions
The following data is based on the product molecular weight 284.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.52 mL | 17.58 mL | 35.17 mL |
| 5 mM | 0.7 mL | 3.52 mL | 7.03 mL |
| 10 mM | 0.35 mL | 1.76 mL | 3.52 mL |
| 50 mM | 0.07 mL | 0.35 mL | 0.7 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Hernandez et al (1993) Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter. Br.J.Pharmacol. 110 1413 PMID: 7905771
Lazareno et al (1990) Characterisation of muscarinic M4 binding sites in rabbit lung, chicken heart and NG 108-15 cells. Mol.Pharmacol. 38 805 PMID: 2250662
Keywords: Tropicamide, supplier, Selective, M4, muscarinic, antagonists, Muscarinic, Receptors, Acetylcholine, ACh, M4, Receptors, M4, Receptors, Tocris Bioscience
