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Tocris/UBP 296/2078/50/50毫克

商品编号： 2078/50

品牌： Tocris Bioscience

市场价： ¥17580.00

美元价： 10548.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Selective,potentkainateantagoNIST;selectiveforGluR5-containingreceptors

ChemicalName:(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveGluR5-subunitcontainingkainatereceptorantagonist(apparentK_D=1.09μM).Displays~90-foldselectivityoverAMPAreceptorsandrecombinanthumanGluR6-andKA2-containingkainatereceptors.HaslittleornoactionatNMDAorgroupImGlureceptors.Selectivelyblockskainatereceptor-mediatedLTPinductioninrathippocampalmossyfibers.ActiveenantiomerUBP302(Cat.No.2079)available.

TechnicalData

M.Wt	333.3
Formula	C₁₅H₁₅N₃O₆
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	745055-86-1
PubChemID	11674376
InChIKey	UUIYULWYHDSXHL-UHFFFAOYSA-N
Smiles	NC(CN1C=CC(=O)N(CC2=C(C=CC=C2)C(O)=O)C1=O)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	1.67	5mMwithgentlewarming
	1eq.NaOH	3.33	10mMwithgentlewarming
	DMSO	3.33	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight333.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3mL	15mL	30mL
5mM	0.6mL	3mL	6mL
10mM	0.3mL	1.5mL	3mL
50mM	0.06mL	0.3mL	0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

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