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Tocris Bioscience(优势品牌)
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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/UBP 310/3621/50/50 mg
商品详细Tocris/UBP 310/3621/50/50 mg
Tocris/UBP 310/3621/50/50 mg
Tocris/UBP 310/3621/50/50 mg
商品编号: 3621/50
品牌: Tocris Bioscience
市场价: ¥13300.00
美元价: 7980.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:GLUK5antagoNIST
ChemicalName:(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GLUK5kainatereceptorantagonist(IC50=130nM);alsoblocksrecombinanthomomericGLUK7receptors.Displays12,700-foldselectivityforGLUK5overGLUK6.ExhibitsnoactivityatmGlugroupIorNMDAreceptorsatconcentrationsofupto10μM.ApparentKDvalueis18±4nMfordepressionofkainateresponsesonthedorsalroot.

CompoundLibraries

UBP310isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt353.35
FormulaC14H15N3O6S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber902464-46-4
PubChemID6420160
InChIKeyZTAZUCRXCRXNSU-VIFPVBQESA-N
SmilesCC1=CN(C[C@@H](C(O)=O)N)C(N(CC2=C(C(O)=O)SC=C2)C1=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.34100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight353.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.83mL14.15mL28.3mL
5mM0.57mL2.83mL5.66mL
10mM0.28mL1.42mL2.83mL
50mM0.06mL0.28mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet