4000-520-616
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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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4000-520-616
当前位置: 首页 > 产品中心 > protease > Tocris/UK 370106/2900/10/10毫克
商品详细Tocris/UK 370106/2900/10/10毫克
Tocris/UK 370106/2900/10/10毫克
Tocris/UK 370106/2900/10/10毫克
商品编号: 2900/10
品牌: Tocris Bioscience
市场价: ¥4500.00
美元价: 2700.00
产地: 美国(厂家直采)
公司:
产品分类: 蛋白酶类
公司分类: protease
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:HighlyselectiveMMP-3andMMP-12inhibitor
ChemicalName:(βR)-β-[[[(1S)-1-[[[(1S)-2-Methoxy-1-phenylethyl]amino]carbonyl]-2,2-dimethylpropyl]amino]carbonyl]-2-methyl-[1,1'-biphenyl]-4-hexanoicacid
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighlyselectiveMMP-3andMMP-12inhibitor(IC50valuesare0.023,0.042,1.75,2.3,5.8,30.4,34.2and66.9μMatMMP3,12,8,13,7,9,2and14respectively.)Inhibitsfibronectincleavage(IC50=320nM)andhaslittleeffectonkeratinocytemigrationinvitro.SubstantiallyinhibitsMMP-3inanexvivomodelofchronicdermalulcers.

TechnicalData

M.Wt572.73
FormulaC35H44N2O5
StorageStoreat-20°C
Purity≥95%(HPLC)
CASNumber230961-21-4
PubChemID9808181
InChIKeyNSMABJUGSNPHMN-BHYWQNONSA-N
SmilesCC(C=C(CCC[C@@H](C(N[C@@H]([C@@](C)(C)C)C(N[C@H](COC)C3=CC=CC=C3)=O)=O)CC(O)=O)C=C2)=C2C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO57.27100
ethanol14.3225

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight572.73.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.75mL8.73mL17.46mL
5mM0.35mL1.75mL3.49mL
10mM0.17mL0.87mL1.75mL
50mM0.03mL0.17mL0.35mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet