Biological Activity
GHB receptor ligand. Exhibits similar receptor afffinity as GHB (IC50 for displacement of 3[H]NCS-382 from GHB receptors is 38 μM compared with 25 μM for GHB). Demonstrates no significant affinity for GABAB receptors and does not exhibit GHB-like behavioral effects in vivo.
Technical Data
| M. Wt | 154.14 |
| Formula | C6H11NaO3 |
| Storage | Desiccate at RT |
| CAS Number | 581099-89-0 |
| PubChem ID | 57340483 |
| InChI Key | RKKDHFJDHVHVLY-UHFFFAOYSA-M |
| Smiles | O=C(CCC(C)(O)C)O[Na] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 15.41 | 100 | |
| DMSO | 15.41 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 154.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.49 mL | 32.44 mL | 64.88 mL |
| 5 mM | 1.3 mL | 6.49 mL | 12.98 mL |
| 10 mM | 0.65 mL | 3.24 mL | 6.49 mL |
| 50 mM | 0.13 mL | 0.65 mL | 1.3 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Wu et al (2003) A tertiary alcohol analog of γ-hydroxybutyric acid as a specific γ-hydroxybutyric acid receptor ligand. J.Pharmacol.Exp.Ther. 305 675 PMID: 12606613
Keywords: UMB 68, supplier, UMB68, gamma-hydroxybutyric, acid, γ, GHB, receptor, ligands, GABAb, GABAB, Receptors, GABAB, Receptors, Tocris Bioscience
