Biological Activity
Selective P2Y2 and P2Y4 receptor agonist. Enzymatically stable.
Technical Data
| M. Wt | 566.15 |
| Formula | C9H12N2Na3O14P3S |
| Storage | Desiccate at -20°C |
| CAS Number | 1266569-94-1 |
| PubChem ID | 54591574 |
| InChI Key | DBXMFBSCFRDIOA-LLWADOMFSA-K |
| Smiles | [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=S)N1C=CC(=O)NC1=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 56.62 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 566.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.77 mL | 8.83 mL | 17.66 mL |
| 5 mM | 0.35 mL | 1.77 mL | 3.53 mL |
| 10 mM | 0.18 mL | 0.88 mL | 1.77 mL |
| 50 mM | 0.04 mL | 0.18 mL | 0.35 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Lazarowski et al (1996) Enzymatic synthesis of UTPγS, a potent hydrolysis resistant agonist of P2U-purinoceptors. Br.J.Pharmacol. 117 203 PMID: 8825364
Malmsjo et al (2000) The stable pyrimidines UDPβS and UTPγS discriminate between the P2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery. Br.J.Pharmacol. 131 51 PMID: 10960068
Malmsjo et al (2003) The stable pyrimidines UDPβS and UTPγS discriminate between contractile cerebrovascular P2 receptors. Eur.J.Pharmacol. 458 305 PMID: 12504787
Keywords: UTPgS trisodium salt, supplier, Selective, P2Y2/4, agonists, Receptors, Purinergic, purinoceptors, UTPgammaS, UTPγS, trisodium, salt, Purinergic, P2Y, Receptors, Purinergic, P2Y, Receptors, Tocris Bioscience
