Tocris/VTP 27999三氟乙酸/5563/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/VTP 27999三氟乙酸/5563/10/10 mg

Tocris/VTP 27999三氟乙酸/5563/10/10 mg

商品编号： 5563/10

品牌： Tocris Bioscience

市场价： ¥4780.00

美元价： 2868.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Highlypotentandselectiverenininhibitor

ChemicalName:MethylN-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamatetrifluoroacetate

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highlypotentandselectiverenininhibitor(IC₅₀=0.47nM).Displays>1000-foldselectivityoverrelatedandunrelatedoff-targets.Blocksrenin-stimulatedERK1/2phosphorylationinvascularsmoothmusclecells.Exhibitsadifferentmodeofactiontoaliskiren(Cat.No.5491).

TechnicalData

M.Wt	639.1
Formula	C₂₆H₄₁ClN₄O₅.CF₃CO₂H
Storage	Storeat-20°C
Purity	≥97%(HPLC)
CASNumber	1013937-63-7
PubChemID	121513870
InChIKey	SYWYSVAEGXHOJO-VIEYARBJSA-N
Smiles	ClC1=CC=CC([C@H](OCCNC(OC)=O)[C@]2([H])CCCN(C(NC[C@@H](NC)C[C@H]3CCCOC3)=O)C2)=C1.OC(C(F)(F)F)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	63.91	100
	water	63.91	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight639.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.56mL	7.82mL	15.65mL
5mM	0.31mL	1.56mL	3.13mL
10mM	0.16mL	0.78mL	1.56mL
50mM	0.03mL	0.16mL	0.31mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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