Tocris/VU 0285683/4381/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/VU 0285683/4381/10/10 mg

Tocris/VU 0285683/4381/10/10 mg

商品编号： 4381/10

品牌： Tocris Bioscience

市场价： ¥3500.00

美元价： 2100.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:NegativeallostericmodulatoratmGlu₅

ChemicalName:3-Fluoro-5-[3-(2-pyridinyl)-1,2,4-oxADIazol-5-yl]-benzonitrile

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

NegativeallostericmodulatorofmGlu₅receptors.DisplayshighaffinityfortheMPEP(Cat.No.1212)bindingsite;actsasafullantagoNISTandblockstheglutamateresponsetomGlu₅(IC₅₀=24.4nM).SelectiveformGlu₅overmGlu₁,mGlu₃andmGlu₄.Exhibitsanxiolyticactivityinrodentmodelsofanxiety.Analogavailable(Cat.No.4323).

TechnicalData

M.Wt	266.23
Formula	C₁₄H₇FN₄O
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	327056-22-4
PubChemID	9816778
InChIKey	GELAFISMURFRCA-UHFFFAOYSA-N
Smiles	FC1=CC(C#N)=CC(C2=NC(C3=NC=CC=C3)=NO2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	13.31	50
	ethanol	6.66	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight266.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.76mL	18.78mL	37.56mL
5mM	0.75mL	3.76mL	7.51mL
10mM	0.38mL	1.88mL	3.76mL
50mM	0.08mL	0.38mL	0.75mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

SolubilityData

PreparingStockSolutions

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