![Tocris/[Arg8]-Vasopressin/2935/1/1 mg](https://www.ebiomall.cn/images/201712/1512520078951260693.jpg)
Biological Activity
Antidiuretic hormone found in most mammalian species. Also acts as a neurotransmitter at synapses in the brain; increases [Ca2+]i in cultured rat hippocampal neurons.
Technical Data
| M. Wt | 1084.23 |
| Formula | C46H65N15O12S2 |
| Sequence |
CYFQNCPRG (Modifications: Disulfide bridge between 1 - 6, Gly-9 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 113-79-1 |
| PubChem ID | 90488786 |
| InChI Key | KBZOIRJILGZLEJ-MCRCNMGXSA-N |
| Smiles | N[C@@H]1CSSC[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC1=O)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 0.50 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 1084.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.92 mL | 4.61 mL | 9.22 mL |
| 5 mM | 0.18 mL | 0.92 mL | 1.84 mL |
| 10 mM | 0.09 mL | 0.46 mL | 0.92 mL |
| 50 mM | 0.02 mL | 0.09 mL | 0.18 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Migara et al (1999) [Arg8]-vasopressin-induced increase in intracellular Ca2+ concentration in cultutred rat hippocampal neurons. Brain Res.Bull. 49 343 PMID: 10452354
Chan et al (2000) Discovery and design of novel and selective vasopressin and oxytocin agonists and antagonists: the role of bioassays. Exp.Physiol. 85S 7S PMID:
Cowley et al (2000) Control of renal medulaary circulation by vasopressin V1 and V2 receptors in the rat. Exp.Physiol. 85S 223S PMID:
Keywords: [Arg8]-Vasopressin, supplier, Antidiuretic, hormone, V2, Receptors, V1, Vasopressin, AVP, Vasopressin, Receptors, Vasopressin, Receptors, Tocris Bioscience
