Tocris/Verteporfin/5305/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Verteporfin/5305/10/10 mg

Tocris/Verteporfin/5305/10/10 mg

商品编号： 5305/10

品牌： Tocris Bioscience

市场价： ¥3380.00

美元价： 2028.00

产地：美国(厂家直采)

公司：

产品分类：转录表达

公司分类： Target_Expression

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:YAPinhibitor;disruptsYAP-TEADinteractions

AlternativeNames:Visudyne

ChemicalName:(4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoicacidmonomethylester

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

YAPinhibitor;disruptsYAP-TEADinteractions.EnhancestrypsincleavageofYAP(EC₅₀=100nM).Inhibitsgrowthandproliferationofretinoblastomacells.Alsosuppressescancerstemcellpropertiesinvitro.SuppressesYAP-inducedliverovergrowthinmice.

TechnicalData

M.Wt	718.79
Formula	C₄₁H₄₂N₄O₈
Storage	Storeat-20°C
Purity	≥97%(HPLC)
CASNumber	129497-78-5
PubChemID	5362420
InChIKey	YTZALCGQUPRCGW-ZSFNYQMMSA-N
Smiles	CC(C(/C=C4N/C([C@@]5(C)C4=CC=C(C(OC)=O)[C@H]5[C@](OC)=O)=CC6=NC(C(CCC(OC)=O)=C6C)=C3)=N2)=C(C=C)/C2=C/C1=C(C)C(CCC(O)=O)=C/3N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	14.38	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight718.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.39mL	6.96mL	13.91mL
5mM	0.28mL	1.39mL	2.78mL
10mM	0.14mL	0.7mL	1.39mL
50mM	0.03mL	0.14mL	0.28mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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