Tocris/XL 413 hydrochloride/5493/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/XL 413 hydrochloride/5493/10/10 mg

Tocris/XL 413 hydrochloride/5493/10/10 mg

商品编号： 5493/10

品牌： Tocris Bioscience

市场价： ¥3980.00

美元价： 2388.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveCdc7inhibitor

AlternativeNames:BMS863233

ChemicalName:8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-onehydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveCdc7inhibitor(IC₅₀=3.4nM).Exhibits>12-foldselectivityforCdc7overPIM-1kinaseand>30-foldselectivityoverpMCMandCK2.InhibitsproliferationofColo205cellsinvitroandattenuatestumorgrowthofColo205xenograftsinmice.

TechnicalData

M.Wt	326.18
Formula	C₁₄H₁₂ClN₃O₂.HCl
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	1169562-71-3
PubChemID	67185304
InChIKey	UNDKJUKLBNARIZ-FVGYRXGTSA-N
Smiles	ClC1=CC=C2C(C(N=[C@@]([C@H]4NCCC4)NC3=O)=C3O2)=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	6.52	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight326.18.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.07mL	15.33mL	30.66mL
5mM	0.61mL	3.07mL	6.13mL
10mM	0.31mL	1.53mL	3.07mL
50mM	0.06mL	0.31mL	0.61mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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