Tocris/ZJ 43/2675/10/10毫克-免疫在线蚂蚁淘旗下平台

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Tocris/ZJ 43/2675/10/10毫克

商品编号： 2675/10

品牌： Tocris Bioscience

市场价： ¥5580.00

美元价： 3348.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:GlutamatecarboxypeptidaseIIandIII(NAALADase,NAAGpeptidase)inhibitor

ChemicalName:N-[[[(1S)-1-Carboxy-3-methylbutyl]amino]carbonyl]-L-glutamicacid

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitorofglutamatecarboxypeptidaseIIandIII(GCPIIandIII/NAAGpeptidase/NAALADase)(K_ivaluesare0.8and23nMrespectively)thatinhibitsthehydrolysisofNAAG(IC₅₀=2.4nM).DoesnotdirectlyinteractwithNMDAormetabotropicglutamatereceptors.Reducesneuronaldegenerationinaratmodelof traumaticbraininjury(TBI)andreduceslocomotoractivityinthePCP-modelofschizophrenia.

LicensingInformation

SoldwiththepermissionofAcentaDiscovery,Inc.

TechnicalData

M.Wt	304.3
Formula	C₁₂H₂₀N₂O₇
Storage	Storeat-20°C
CASNumber	723331-20-2
PubChemID	11722553
InChIKey	BSGWCSGMXAVYRT-YUMQZZPRSA-N
Smiles	CC(C[C@@]([H])(C(O)=O)NC(N[C@@]([H])(CCC(O)=O)C(O)=O)=O)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	30.43	100
	water	30.43	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight304.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.29mL	16.43mL	32.86mL
5mM	0.66mL	3.29mL	6.57mL
10mM	0.33mL	1.64mL	3.29mL
50mM	0.07mL	0.33mL	0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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