Tocris/ZM 449829/1366/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/ZM 449829/1366/10/10 mg

Tocris/ZM 449829/1366/10/10 mg

商品编号： 1366/10

品牌： Tocris Bioscience

市场价： ¥2780.00

美元价： 1668.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potent,selectiveJAK3inhibitor

ChemicalName:1-(2-Naphthalenyl)-2-propen-1-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveinhibitorofJanustyrosinekinase3(JAK3)whichbindscompetitivelytotheJAK3ATPsite.pIC₅₀valuesare6.8,5.0,4.7,and<5.0forJAK3,EGFR,JAK1andCDK4respectively.InhibitsSTAT-5phosphorylationandTcellproliferation.

LicensingInformation

SoldwiththepermissionofAstraZenecaLtd.

TechnicalData

M.Wt	182.22
Formula	C₁₃H₁₀O
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	4452-06-6
PubChemID	3799
InChIKey	FOTCGZPFSUWZBN-UHFFFAOYSA-N
Smiles	C=CC(C2=CC1=CC=CC=C1C=C2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	18.22	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight182.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	5.49mL	27.44mL	54.88mL
5mM	1.1mL	5.49mL	10.98mL
10mM	0.55mL	2.74mL	5.49mL
50mM	0.11mL	0.55mL	1.1mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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