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Tocris Bioscience(优势品牌)
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/Zoledronic Acid/6111/10/10 mg
商品详细Tocris/Zoledronic Acid/6111/10/10 mg
Tocris/Zoledronic Acid/6111/10/10 mg
Tocris/Zoledronic Acid/6111/10/10 mg
商品编号: 6111/10
品牌: Tocris Bioscience
市场价: ¥1380.00
美元价: 828.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potentfarnesyldiphosphate(FPP)synthaseinhibitor
AlternativeNames:Zometa
ChemicalName:[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentbisphophonatefarnesyldiphosphate(FPP)synthaseinhibitor(IC50=20nM).Inhibitsosteoclast-mediatedboneresorption.AlsoinhibitsRassignalingandtumorgrowth,andinducesapoptosisinpancreaticcancercells.Reversesepithelial-mesenchymaltransitionandinhibitsbreastcancercellrenewalviainactivationofNF-κB.

TechnicalData

M.Wt272.09
FormulaC5H10N2O7P2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber118072-93-8
PubChemID68740
InChIKeyXRASPMIURGNCCH-UHFFFAOYSA-N
SmilesOC(P(O)(O)=O)(P(O)(O)=O)CN1C=CN=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water0.682.5
1.1eq.NaOH13.650

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight272.09.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.68mL18.38mL36.75mL
5mM0.74mL3.68mL7.35mL
10mM0.37mL1.84mL3.68mL
50mM0.07mL0.37mL0.74mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet