Tocris/XMD 8-87/6061/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/XMD 8-87/6061/50/50 mg

Tocris/XMD 8-87/6061/50/50 mg

商品编号： 6061/50

品牌： Tocris Bioscience

市场价： ¥15900.00

美元价： 9540.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:PotentAck1/TNK2inhibitor

ChemicalName:5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentAck1/TNK2inhibitor(IC₅₀=38and113nMinBa/F3celllinescontainingleukemia-associatedD163EandR806Qmutationsrespectively).BlocksphosphorylationofTNK2receptorscontainingsolid-tumortypetruncationmutations.

LicensingInformation

SoldunderlicensefromDana-FarberCancerInstitute.

CompoundLibraries

XMD8-87isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	445.52
Formula	C₂₄H₂₇N₇O₂
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	1234480-46-6
PubChemID	53322923
InChIKey	LGLHCXISMKHLIK-UHFFFAOYSA-N
Smiles	COC1=C(C=CC(N2CCN(CC2)C)=C1)NC3=NC=C4NC(C5=CC=CC=C5N(C4=N3)C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	44.55	100
	DMSO	22.28	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight445.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.24mL	11.22mL	22.45mL
5mM	0.45mL	2.24mL	4.49mL
10mM	0.22mL	1.12mL	2.24mL
50mM	0.04mL	0.22mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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