Tocris/ML 315 hydrochloride/5700/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/ML 315 hydrochloride/5700/50/50 mg

Tocris/ML 315 hydrochloride/5700/50/50 mg

商品编号： 5700/50

品牌： Tocris Bioscience

市场价： ¥15900.00

美元价： 9540.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitorofClkandDYRKkinases

ChemicalName:5-(1,3-Benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-4-pyrimidinaminehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofcdc2-likekinases(Clk)andDYRKkinases(IC₅₀valuesare68,68and231nMforClk1,Clk4andClk2,respectively,and282and1156nMforDyrk1AandDyrk1B).Shows20-foldselectivityforClk4overDyrk1A.Stableinbothmouseandhumanplasma.Moderatelycellpermeable.

TechnicalData

M.Wt	410.68
Formula	C₁₈H₁₃Cl₂N₃O₂.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1440251-53-5
PubChemID	127021037
InChIKey	MNCDEAAKKQCKSX-UHFFFAOYSA-N
Smiles	ClC1=CC(CNC2=NC=NC=C2C3=CC=C(OCO4)C4=C3)=CC(Cl)=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	37.42	100
	ethanol	18.71	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight410.68.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.43mL	12.17mL	24.35mL
5mM	0.49mL	2.43mL	4.87mL
10mM	0.24mL	1.22mL	2.43mL
50mM	0.05mL	0.24mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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