Tocris/A 331440二氢氯化物/4697/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/A 331440二氢氯化物/4697/10/10 mg

Tocris/A 331440二氢氯化物/4697/10/10 mg

商品编号： 4697/10

品牌： Tocris Bioscience

市场价： ¥3980.00

美元价： 2388.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveH₃antagoNIST

ChemicalName:4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitriledihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityhistamineH₃receptorantagonist(K_ivaluesare21.7and22.7nMforratandhumanH₃receptors,respectively).ExhibitsselectivityforhumanH₃overH₁,H₂andH₄receptors(K_ivaluesare2940,14400and>10000nMrespectively).Showntoreduceweightinadiet-inducedobesitymodel.

TechnicalData

M.Wt	422.39
Formula	C₂₂H₂₇N₃O.2HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
CASNumber	1049740-32-0
PubChemID	16078942
InChIKey	XFPYVTSGYYMTFS-GHVWMZMZSA-N
Smiles	CN(C)[C@H](CC3)CN3CCCOC1=CC=C(C2=CC=C(C#N)C=C2)C=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	8.45	20
	water	42.24	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight422.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.37mL	11.84mL	23.67mL
5mM	0.47mL	2.37mL	4.73mL
10mM	0.24mL	1.18mL	2.37mL
50mM	0.05mL	0.24mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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