Tocris/A 419259三盐酸盐/3914/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/A 419259三盐酸盐/3914/10/10 mg

Tocris/A 419259三盐酸盐/3914/10/10 mg

商品编号： 3914/10

品牌： Tocris Bioscience

市场价： ¥5580.00

美元价： 3348.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitorofSrcfamilykinases

ChemicalName:7-[trans-4-(4-Methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-Pyrrolo[2,3-d]pyrimidin-4-aminetrihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentHckinhibitor(IC₅₀=0.43nM).AlsoinhibitsotherSrcfamilykinases(SFKs).SuppressesproliferationandinducesapoptosisinCMLcelllinesincludingCD34⁺.Alsoinhibitsacutemyeloidleukemia(AML)stemcellproliferationinvitroandinvivo.

TechnicalData

M.Wt	592.01
Formula	C₂₉H₃₄N₆O.3HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
CASNumber	1435934-25-0
PubChemID	76848881
InChIKey	ALRMEQIQFCUAMR-UHFFFAOYSA-N
Smiles	NC1=C2C(N([C@H]5CC[C@H](N6CCN(C)CC6)CC5)C=C2C3=CC=C(OC4=CC=CC=C4)C=C3)=NC=N1.Cl.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	59.2	100
	water	59.2	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight592.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.69mL	8.45mL	16.89mL
5mM	0.34mL	1.69mL	3.38mL
10mM	0.17mL	0.84mL	1.69mL
50mM	0.03mL	0.17mL	0.34mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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