Tocris/A 740003/3701/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/A 740003/3701/10/10 mg

Tocris/A 740003/3701/10/10 mg

商品编号： 3701/10

品牌： Tocris Bioscience

市场价： ¥3380.00

美元价： 2028.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveP2X₇antagoNIST

ChemicalName:N-[1-[[(Cyanoamino)(5-quinolinylamino)methylene]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveP2X₇receptorantagonist(IC₅₀valuesare18and40nMforratandhumanreceptorsrespectively).DisplaysselectivityoveravarietyofP2XandP2Yreceptorsuptoaconcentrationof100μM.Reducesnociceptioninanimalmodelsofpersistentneuropathicandinflammatorypain.Alsoreducesneuroblastomatumorgrowthinmice.

CompoundLibraries

A740003isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	474.55
Formula	C₂₆H₃₀N₆O₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	861393-28-4
PubChemID	11351968
InChIKey	PUHSRMSFDASMAE-UHFFFAOYSA-N
Smiles	CC(C)(C)C(NC(CC3=CC(OC)=C(OC)C=C3)=O)N/C(NC2=CC=CC1=NC=CC=C12)=N/C#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	9.49	20
	ethanol	2.37	5mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight474.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.11mL	10.54mL	21.07mL
5mM	0.42mL	2.11mL	4.21mL
10mM	0.21mL	1.05mL	2.11mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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