Tocris/A 804598/4473/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/A 804598/4473/10/10 mg

Tocris/A 804598/4473/10/10 mg

商品编号： 4473/10

品牌： Tocris Bioscience

市场价： ¥3380.00

美元价： 2028.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveP2X₇antagoNIST

ChemicalName:N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,competitiveP2X₇receptorantagonist(IC₅₀valuesare8.9,9.9and10.9nMformouse,ratandhumanP2X₇receptorsrespectively).SelectiveforP2X₇receptors(IC₅₀>5-10μMforawidearrayofcellsurfacereceptorsandionchannels).Bindswithhighaffinity(K_iapp=2.4nMforratP2X₇receptors).

CompoundLibraries

A804598isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	315.37
Formula	C₁₉H₁₇N₅
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	1125758-85-1
PubChemID	53325874
InChIKey	PQYCRDPLPKGSME-AWEZNQCLSA-N
Smiles	C[C@@H](C3=CC=CC=C3)NC(NC2=CC=CC1=NC=CC=C12)=NC#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	31.54	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight315.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.17mL	15.85mL	31.71mL
5mM	0.63mL	3.17mL	6.34mL
10mM	0.32mL	1.59mL	3.17mL
50mM	0.06mL	0.32mL	0.63mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets