Tocris/A 867744/4571/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/A 867744/4571/50/50 mg

Tocris/A 867744/4571/50/50 mg

商品编号： 4571/50

品牌： Tocris Bioscience

市场价： ¥15100.00

美元价： 9060.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Positiveallostericmodulatorofα7nAChR

ChemicalName:4-[5-(4-Chlorophenyl)-2-methyl-3-(1-oxopropyl)-1H-pyrrol-1-yl]benzenesulfonamide

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Positiveallostericmodulatorofα7nAChRs(IC₅₀valuesare0.98and1.12μMforhumanandratα7receptorACh-evokedcurrentsrespectively,inX.laevisoocytes).Displaysnoactivityat5-HT_3A,α3β4orα4β2nAChRs.Brainpenetrant.

CompoundLibraries

A867744isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	402.89
Formula	C₂₀H₁₉ClN₂O₃S
Storage	Storeat+4°C
Purity	≥97%(HPLC)
CASNumber	1000279-69-5
PubChemID	23642319
InChIKey	ABACVOXFUHDKNZ-UHFFFAOYSA-N
Smiles	O=C(CC)C1=C(C)N(C3=CC=C(S(N)(=O)=O)C=C3)C(C2=CC=C(Cl)C=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	40.29	100
	ethanol	4.03	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight402.89.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.48mL	12.41mL	24.82mL
5mM	0.5mL	2.48mL	4.96mL
10mM	0.25mL	1.24mL	2.48mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

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ProductDatasheets