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Tocris Bioscience(优势品牌)
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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/A 887826/4249/10/10 mg
商品详细Tocris/A 887826/4249/10/10 mg
Tocris/A 887826/4249/10/10 mg
Tocris/A 887826/4249/10/10 mg
商品编号: 4249/10
品牌: Tocris Bioscience
市场价: ¥3780.00
美元价: 2268.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potentvoltage-dependentNaV1.8channelblocker
ChemicalName:5-(4-Butoxy-3-chlorophenyl)-N-[[2-(4-morpholinyl)-3-pyridinyl]methyl-3-pyridinecarboxamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentvoltage-dependentNaV1.8channelblocker(IC50=11nMinrecombinanthumanNaV1.8channels).Reducestactileallodyniainneuropathicratmodels.3-and28-foldmorepotentatNaV1.8channelscomparedtoNaV1.2andNaV1.7channelsrespectively.

CompoundLibraries

A887826isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt480.99
FormulaC26H29ClN4O3
StorageStoreatRT
Purity≥97%(HPLC)
CASNumber1266212-81-0
PubChemID46919335
InChIKeyJPJGFWKHSMUKFO-UHFFFAOYSA-N
SmilesClC1=C(OCCCC)C=CC(C2=CN=CC(C(NCC3=CC=CN=C3N4CCOCC4)=O)=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.0550

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight480.99.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.08mL10.4mL20.79mL
5mM0.42mL2.08mL4.16mL
10mM0.21mL1.04mL2.08mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet