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Tocris Bioscience(优势品牌)
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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/A 967079/4716/50/50 mg
商品详细Tocris/A 967079/4716/50/50 mg
Tocris/A 967079/4716/50/50 mg
Tocris/A 967079/4716/50/50 mg
商品编号: 4716/50
品牌: Tocris Bioscience
市场价: ¥11700.00
美元价: 7020.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:SelectiveTRPA1channelblocker
ChemicalName:(1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-pentene-3-oneoxime
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveTRPA1channelblocker(IC50valuesare67and289nMathumanandratTRPA1receptorsrespectively).Displays1000-foldselectivityforTRPA1overotherTRPchannels,andis>150-foldselectiveover75otherionchannels,enzymesandG-protein-coupledreceptors.Exhibitsanalgesiceffectsinaratosteoarthriticpainmodel.

CompoundLibraries

A967079isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt207.24
FormulaC12H14FNO
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1170613-55-4
PubChemID42641861
InChIKeyHKROEBDHHKMNBZ-CHBKHGQFSA-N
SmilesFC1=CC=C(/C=C(C)/C(CC)=N/O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO20.72100
ethanol20.72100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight207.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.83mL24.13mL48.25mL
5mM0.97mL4.83mL9.65mL
10mM0.48mL2.41mL4.83mL
50mM0.1mL0.48mL0.97mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet