Tocris/A12B4C3/5097/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/A12B4C3/5097/50/50 mg

Tocris/A12B4C3/5097/50/50 mg

商品编号： 5097/50

品牌： Tocris Bioscience

市场价： ¥19300.00

美元价： 11580.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentandselectivepolynucleotidekinase/phosphatase(PNKP)inhibitor

ChemicalName:4a,7a-Dihydro-2-(1-hydroxyundecyl)-1-[(4-nitrophenyl)amino]-6-phenyl-1H-pyrrolo[3,4-b]pyridine-5,7(2H,6H)-dione

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivepolynucleotidekinase/phosphatase(PNKP)inhibitor(IC₅₀=60nM).Displaysnoeffectoncalcineurin,proteinPP-1orAPTX.InterruptsDNArepairandenhancesrADIosensitivityofhumanA549lungcarcinomaandMDA-MB-231cells.

CompoundLibraries

A12B4C3isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	534.65
Formula	C₃₀H₃₈N₄O₅
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1005129-80-5
PubChemID	6610064
InChIKey	KVHGJAKTBPFFNV-UHFFFAOYSA-N
Smiles	O=C2N(C4=CC=CC=C4)C(C1C=CC(C(O)CCCCCCCCCC)N(NC3=CC=C([N+]([O-])=O)C=C3)C12)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	53.47	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight534.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.87mL	9.35mL	18.7mL
5mM	0.37mL	1.87mL	3.74mL
10mM	0.19mL	0.94mL	1.87mL
50mM	0.04mL	0.19mL	0.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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SolubilityData

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