Tocris/A66/5595/50/50毫克-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > Other_enzymes > Tocris/A66/5595/50/50毫克

商品详细Tocris/A66/5595/50/50毫克

Tocris/A66/5595/50/50毫克

商品编号： 5595/50

品牌： Tocris Bioscience

市场价： ¥12580.00

美元价： 7548.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:PotentandselectivePI3-kinasep110αinhibitor

ChemicalName:(2S)-N¹-[2-(1,1-Dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivePI3-kinasep110αinhibitor(IC₅₀=32nM).Exhibits>100-foldselectivityforp110αoverotherPI3-kinaseisoforms.InhibitsAktsignalingandtumorgrowthinSK-OV-3xenograftsinmice.

CompoundLibraries

A66isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	393.53
Formula	C₁₇H₂₃N₅O₂S₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1166227-08-2
PubChemID	42636535
InChIKey	HBPXWEPKNBHKAX-NSHDSACASA-N
Smiles	CC(C)(C)C1=NC(C2=C(C)N=C(NC(N3[C@H](C(N)=O)CCC3)=O)S2)=CS1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	39.35	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight393.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.54mL	12.71mL	25.41mL
5mM	0.51mL	2.54mL	5.08mL
10mM	0.25mL	1.27mL	2.54mL
50mM	0.05mL	0.25mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage:

BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets