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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/ABT 089二氢氯化物/5079/10/10 mg
商品详细Tocris/ABT 089二氢氯化物/5079/10/10 mg
Tocris/ABT 089二氢氯化物/5079/10/10 mg
Tocris/ABT 089二氢氯化物/5079/10/10 mg
商品编号: 5079/10
品牌: Tocris Bioscience
市场价: ¥3580.00
美元价: 2148.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Highaffinityandselectiveα4β2partialagoNIST
ChemicalName:2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridinedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highaffinityandselectiveα4β2partialagonist(Ki=16nM).Exhibits>1000-foldand>10,000-foldselectivityforα4β2overα1β1γ1andα7receptorsrespectively.Neuroprotectiveagainstglutamate-inducedtoxicityinratcorticalneuronsinvitro.Enhancescognitiveperformanceinvivo.Orallybioavailableandbrainpenetrant.

TechnicalData

M.Wt265.18
FormulaC11H16N2O.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber161416-61-1
PubChemID23729426
InChIKeyUGVSESCRKJTJAK-XRIOVQLTSA-N
SmilesCC1=NC=CC=C1OC[C@H]2NCCC2.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO5.320
water26.52100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight265.18.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.77mL18.86mL37.71mL
5mM0.75mL3.77mL7.54mL
10mM0.38mL1.89mL3.77mL
50mM0.08mL0.38mL0.75mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet