Tocris/AEG 3482/2651/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/AEG 3482/2651/10/10 mg

Tocris/AEG 3482/2651/10/10 mg

商品编号： 2651/10

品牌： Tocris Bioscience

市场价： ¥2580.00

美元价： 1548.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitorofJNKsignaling

ChemicalName:6-Phenylimidazo[2,1-b]-1,3,4-thiADIazole-2-sulfonamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofc-junN-terminalkinase(JNK)signaling.BindsHsp90andfacilitatesHSF1release,inducesexpressionofHsp70,whichinturnblocksJNKactivationandJNK-dependentapoptosis.Antiapoptotic;inhibitsNGFwithdrawal-induceddeathinSCGneurons(EC₅₀=20μM).

CompoundLibraries

AEG3482isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	280.33
Formula	C₁₀H₈N₄O₂S₂
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	63735-71-7
PubChemID	698112
InChIKey	MQUYTXDAVCOCMX-UHFFFAOYSA-N
Smiles	NS(=O)(=O)C1=NN2C=C(N=C2S1)C1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	28.03	100
	ethanol	1.4	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight280.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.57mL	17.84mL	35.67mL
5mM	0.71mL	3.57mL	7.13mL
10mM	0.36mL	1.78mL	3.57mL
50mM	0.07mL	0.36mL	0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets