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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > kinase > Tocris/AG 1478盐酸盐/1276/10/10毫克
商品详细Tocris/AG 1478盐酸盐/1276/10/10毫克
Tocris/AG 1478盐酸盐/1276/10/10毫克
Tocris/AG 1478盐酸盐/1276/10/10毫克
商品编号: 1276/10
品牌: Tocris Bioscience
市场价: ¥3180.00
美元价: 1908.00
产地: 美国(厂家直采)
公司:
产品分类: 激酶
公司分类: kinase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:HighlypotentEGFR-kinaseinhibitor
AlternativeNames:TyrphostinAG1478
ChemicalName:N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinaninehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectiveinhibitorofepidermalgrowthfactorreceptorkinase(IC50values3nMforEGFRand>100μMforErbB2andPDGFR).InhibitsproliferationofNCI-H2170NSCLCcellsinvitro(IC50=1μM).

LicensingInformation

SoldwiththepermissionofAstraZenecaUKLtd.

TechnicalData

M.Wt352.22
FormulaC16H14ClN3O2.HCl
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber170449-18-0
PubChemID3035187
InChIKeyWDJDYIUSDDVWKB-UHFFFAOYSA-N
SmilesClC1=CC(NC2=NC=NC3=C2C=C(OC)C(OC)=C3)=CC=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO3.5210mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight352.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.84mL14.2mL28.39mL
5mM0.57mL2.84mL5.68mL
10mM0.28mL1.42mL2.84mL
50mM0.06mL0.28mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet